What is the Monkeypox (Poxvirus) virus? Monkeypox is a zoonotic disease that is caused by infection with the monkeypox virus (MPV) . The condition is characterized by severe skin disease and high morbidity and mortality. The natural reservoir for the virus is the monkey and possibly other mammals, but humans are the only known host. Monkeypox virus, a member of the Orthopoxvirus family , is a small, non-enveloped, single-stranded, negative-sense RNA virus of the Phycodnaviridae family that causes a disease in monkeys and other primates. Monkeypox is a member of the orthopoxvirus family, and it causes a disease in humans that is clinically similar to smallpox. The virus was first isolated from monkeys in 1958 , and it was recognized as an important human pathogen in 1970. The majority of cases occur in Africa , but monkeypox has been reported worldwide. Virus Monkeypox virus is a member of the Orthopoxvirus genus of the Poxviridae family. It causes monkeypox, a rare viral disease in hu
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